SCHEMBL14252146

SCHEMBL14252146

CCc1cc(CC)cc(SC)c1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.36
SLC6A4 P31645 9/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
TP53 P04637 1/20 0.33
MAOA P21397 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A3 Q01959 1/20 0.32
TRPA1 O75762 1/20 0.32
SIGMAR1 Q99720 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12410575 0.94 PTGS2 (0.36) PTGS2SLC6A4KDM4EMEN1KMT2A
SCHEMBL16961149 0.89 ACHE (0.36) PTGS2SLC6A4KDM4EMEN1KMT2A
SCHEMBL16958968 0.85 MEN1 (0.32) PTGS2SLC6A4KDM4EMEN1KMT2A
SCHEMBL16958964 0.84 PTGS2 (0.30) PTGS2KDM4EMEN1KMT2AATM
SCHEMBL12075872 0.80 MAOA (0.38) PTGS2MAOA
SCHEMBL23841182 0.80 HSPA5 (0.34)
SCHEMBL16960480 0.80 SIGMAR1 (0.32) KDM4EMEN1KMT2AATMSMN1; SMN2
SCHEMBL22434950 0.80 SLC6A4 (0.33) SLC6A4MAOASLC6A2SLC6A3
SCHEMBL13189259 0.80 PTGS2 (0.41) PTGS2SLC6A4KDM4EMEN1KMT2A
SCHEMBL9488415 0.80 PTGS2 (0.37) PTGS2RXRARXRBTP53TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7343073-B2 Optical members and compositions for producing them FUJIFILM CORPORATION (JP) 2008-03-11 US disclosed
US-7343073-B2 Optical members and compositions for producing them FUJIFILM CORPORATION (JP) 2008-03-11 US disclosed