Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | GBA1 | P04062 | 2/20 | 0.56 |
| ▸ | CCR4 | P51679 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14256796 | 0.91 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2APKMLMNA | |
| SCHEMBL14266665 | 0.84 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2APKMLMNA | |
| SCHEMBL14256461 | 0.83 | HSD17B10 (0.78) | ALDH1A1MEN1KMT2APKMLMNA | |
| SCHEMBL14256772 | 0.83 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2APKMLMNA | |
| SCHEMBL14256626 | 0.81 | KDM4E (0.77) | ALDH1A1MEN1KMT2APKMLMNA | |
| SCHEMBL14256519 | 0.81 | KDM4E (0.74) | ALDH1A1MEN1KMT2APKMLMNA | |
| SCHEMBL14256521 | 0.80 | CYP3A4 (0.58) | ALDH1A1MEN1KMT2APKMLMNA | |
| SCHEMBL14256769 | 0.80 | KMT2A (0.61) | ALDH1A1MEN1KMT2APKMLMNA | |
| SCHEMBL14256553 | 0.79 | CCR4 (0.60) | ALDH1A1MEN1KMT2APKMLMNA | |
| SCHEMBL14256631 | 0.75 | CCR4 (0.71) | ALDH1A1MEN1KMT2APKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058312-A1 | Modulators of hepatocyte growth factor/c-Met activity | ANGION BIOMEDICA CORPORATION (US) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058312-A1 | Modulators of hepatocyte growth factor/c-Met activity | HGF, MET, HDGF | ALDH1A1 823/4885MEN1 913/4885KMT2A 1715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.