Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 5/20 | 0.57 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.57 |
| ▸ | PDK3 | Q15120 | 5/20 | 0.57 |
| ▸ | PDK4 | Q16654 | 5/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14263246 | 0.90 | S1PR1 (0.58) | PDK1PDK2PDK3PDK4S1PR4 | |
| SCHEMBL14263188 | 0.86 | PDK1 (0.64) | PDK1PDK2PDK3PDK4S1PR4 | |
| SCHEMBL11039994 | 0.84 | L3MBTL1 (0.50) | PDK1PDK2PDK3PDK4S1PR1 | |
| SCHEMBL14263296 | 0.84 | S1PR1 (0.54) | S1PR4S1PR1S1PR3S1PR5HDAC1 | |
| SCHEMBL28927912 | 0.83 | MMP8 (0.63) | PDK1PDK2PDK3PDK4MMP8 | |
| SCHEMBL4984163 | 0.83 | S1PR1 (0.71) | PDK1PDK2PDK3PDK4S1PR4 | |
| SCHEMBL4984174 | 0.83 | S1PR1 (0.71) | PDK1PDK2PDK3PDK4S1PR4 | |
| SCHEMBL14263212 | 0.83 | S1PR4 (0.52) | S1PR4S1PR1S1PR3S1PR5L3MBTL1 | |
| SCHEMBL5358576 | 0.83 | S1PR1 (0.71) | PDK1PDK2PDK3PDK4S1PR4 | |
| SCHEMBL3295838 | 0.81 | PDK1 (0.61) | PDK1PDK2PDK3PDK4MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064662-A1 | Methods and compositions for modulating sphingosine -1- phosphate (S1P) receptor activity | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064662-A1 | Methods and compositions for modulating sphingosine -1- phosphate (S1P) receptor activity | S1PR1, S1PR2, S1PR3 | PDK1 1262/4885PDK2 2197/4885PDK3 2350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.