Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | MME | P08473 | 7/20 | 0.50 |
| ▸ | ACE | P12821 | 7/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.49 |
| ▸ | CPA1 | P15085 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4468791 | 0.87 | MME (0.63) | PTPN1MMEACEACE2CPA1 | |
| SCHEMBL13537467 | 0.87 | MME (0.63) | PTPN1MMEACEACE2CPA1 | |
| SCHEMBL5943645 | 0.87 | MME (0.63) | PTPN1MMEACEACE2CPA1 | |
| SCHEMBL10626666 | 0.85 | LMNA (0.56) | PTPN1PPARGMMEACEACE2 | |
| SCHEMBL10622597 | 0.85 | LMNA (0.56) | PTPN1PPARGMMEACEACE2 | |
| SCHEMBL2615852 | 0.85 | LMNA (0.56) | PTPN1PPARGMMEACEACE2 | |
| SCHEMBL2099399 | 0.81 | NPSR1 (0.56) | PTPN1PPARGMMEACEACE2 | |
| SCHEMBL2099396 | 0.81 | NPSR1 (0.56) | PTPN1PPARGMMEACEACE2 | |
| SCHEMBL28470379 | 0.80 | PPARG (0.72) | PTPN1PPARG | |
| SCHEMBL9005835 | 0.78 | PPARA (0.74) | PTPN1PPARGACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348437-B2 | Proteomic analysis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-03-25 | — | — | US | disclosed |