SCHEMBL5943645

SCHEMBL5943645

BC(=O)NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 3/20 0.63
▸ NPSR1 Q6W5P4 1/20 0.61
▸ NAALAD2 Q9Y3Q0 2/20 0.59
▸ L3MBTL1 Q9Y468 1/20 0.58
▸ ACE P12821 2/20 0.56
▸ CPA1 P15085 2/20 0.56
▸ ACE2 Q9BYF1 2/20 0.56
▸ FPR2 P25090 5/20 0.55
▸ PTPN1 P18031 1/20 0.55
▸ FOLH1 Q04609 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4468791 1.00 MME (0.63) MMENPSR1NAALAD2L3MBTL1ACE
SCHEMBL13537467 1.00 MME (0.63) MMENPSR1NAALAD2L3MBTL1ACE
SCHEMBL14263358 0.87 PTPN1 (0.55) MMENPSR1NAALAD2ACECPA1
SCHEMBL15743886 0.86 HPGDS (0.53) MME
SCHEMBL13536303 0.86 ALDH1A1 (0.55) MMEL3MBTL1
SCHEMBL1696507 0.85 MME (0.67) MMENPSR1NAALAD2L3MBTL1ACE
SCHEMBL18180178 0.85 NAALAD2 (0.78) MMENPSR1NAALAD2L3MBTL1FPR2
SCHEMBL547223 0.85 MME (0.67) MMENPSR1NAALAD2L3MBTL1ACE
SCHEMBL19969196 0.85 NAALAD2 (0.78) MMENPSR1NAALAD2L3MBTL1FPR2
SCHEMBL547222 0.85 MME (0.67) MMENPSR1NAALAD2L3MBTL1ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2315740-B1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES CATABASIS PHARMACEUTICALS INC (US) 2017-10-25 — — EP disclosed
EP-2813486-B1 Fatty acid acetylated salicylates and their uses CATABASIS PHARMACEUTICALS INC (US) 2017-10-25 — — EP disclosed
US-20170246193-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. 2017-08-31 — — US disclosed
US-9458094-B2 Fatty acid acetylated salicylates and their uses CATABASIS PHARMACEUTICALS, INC. (US) 2016-10-04 — — US disclosed
US-9272984-B2 Fatty acid acetylated salicylates and their uses CATABASIS PHARMACEUTICALS, INC. (US) 2016-03-01 — — US disclosed
US-20150099723-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. (US) 2015-04-09 — — US disclosed
EP-2813486-A1 Fatty acid acetylated salicylates and their uses Catabasis Pharmaceuticals, Inc. (US) 2014-12-17 — — EP disclosed
US-20140221323-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. (US) 2014-08-07 — — US disclosed
US-8735379-B2 Fatty acid acetylated salicylates and their uses CATABASIS PHARMACEUTICALS, INC. (US) 2014-05-27 — — US disclosed
US-8729293-B2 Fatty acid acetylated salicylates and their uses CATABASIS PHARMACEUTICALS, INC. (US) 2014-05-20 — — US disclosed
US-8173831-B2 Fatty acid acetylated salicylates and their uses CATABASIS PHARMACEUTICALS, INC. (US) 2012-05-08 — — US disclosed
US-20100041748-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. 2010-02-18 — — US disclosed
US-7649015-B2 Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds GILEAD SCIENCES, INC. (US) 2010-01-19 — — US disclosed
US-20070010489-A1 Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds GILEAD SCIENCES, INC. 2007-01-11 — — US disclosed
US-20070010489-A1 Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds GILEAD SCIENCES, INC. 2007-01-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150099723-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES FASN, ACACA, FABP4 MME 2755/4885NPSR1 2031/4885NAALAD2 238/4885
US-20170246193-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES FASN, ACACA, FABP4 MME 2755/4885NPSR1 2031/4885NAALAD2 238/4885
US-20100041748-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES FASN, ACACA, FABP4 MME 2755/4885NPSR1 2031/4885NAALAD2 238/4885
US-20140221323-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES FASN, ACACA, FABP4 MME 2755/4885NPSR1 2031/4885NAALAD2 238/4885
US-20070010489-A1 Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds PPA1, PNP, PPME1 MME 145/4885NPSR1 4160/4885NAALAD2 76/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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