Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PAX2 | Q02962 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14410614 | 0.90 | PAX2 (0.47) | KDM4EPKMPAX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL976753 | 0.82 | ALDH1A1 (0.44) | KDM4EPAX2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5593192 | 0.80 | PAX2 (0.43) | KDM4EPAX2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL14490813 | 0.80 | KDM4E (0.59) | KDM4EPKMPAX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL24129395 | 0.80 | PAX2 (0.61) | KDM4EPAX2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL24129343 | 0.78 | PAX2 (0.63) | KDM4EPAX2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL14271003 | 0.78 | KDM4E (0.48) | KDM4EPKMPAX2ALDH1A1TSHR | |
| SCHEMBL14491201 | 0.77 | ALDH1A1 (0.46) | KDM4EPAX2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL14490818 | 0.77 | KDM4E (0.56) | KDM4EPKMPAX2ALDH1A1TSHR | |
| SCHEMBL14490810 | 0.77 | KDM4E (0.56) | KDM4EPKMPAX2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039319-A1 | Fungicidal Mixtures and Novel Triazolopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039319-A1 | Fungicidal Mixtures and Novel Triazolopyrimidines | ATIC, ARSA, AOC1 | KDM4E 1201/4885PKM 1324/4885PAX2 4611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.