SCHEMBL14273632

SCHEMBL14273632

C#CCCCC(=O)OCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.55
GAA P10253 2/20 0.44
MGAM O43451 1/20 0.44
SI P14410 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44
NR1I2 O75469 1/20 0.44
PGR P06401 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
PTGS2 P35354 1/20 0.44
PDE4D Q08499 1/20 0.44
HSD17B10 Q99714 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CNR1 P21554 2/20 0.42
CNR2 P34972 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15902588 0.94 CYP1A2 (0.53) CYP1A2GAAMGAMSIMGAM2
SCHEMBL21052403 0.92 MAPT (0.53) CYP1A2GAAMGAMSIMGAM2
SCHEMBL13734761 0.92 MAPT (0.53) CYP1A2GAAMGAMSIMGAM2
SCHEMBL31264375 0.92 MAPT (0.53) CYP1A2GAAMGAMSIMGAM2
SCHEMBL101402 0.87
SCHEMBL21645058 0.84 CYP1A2 (0.44) CYP1A2GAAMGAMSIMGAM2
SCHEMBL19362798 0.82 DGKA (0.55) ALDH1A1TSHRTDP1CNR1CNR2
SCHEMBL10011030 0.82 L3MBTL1 (0.58) CYP1A2GAAMGAMSIMGAM2
SCHEMBL10012032 0.82 GSTP1 (0.56) CYP1A2GAAMGAMSIMGAM2
SCHEMBL1702581 0.81 CYP1A2 (0.57) CYP1A2GAAMGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102501-A1 ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS NUVATION BIO INC (US) 2026-04-16 US disclosed
EP-4720051-A1 IONIZABLE LIPIDS Bristol-Myers Squibb Company (US) 2026-04-08 EP disclosed
US-12440466-B2 Fatty acid derivatives for treating non-alcoholic steatohepatitis BASF AS (NO) 2025-10-14 US disclosed
EP-4593824-A2 ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS Nuvation Bio Inc. (US) 2025-08-06 EP disclosed
US-20240390284-A1 IONIZABLE LIPIDS BRISTOL-MYERS SQUIBB COMPANY (US) 2024-11-28 US disclosed
WO-2024243480-A1 IONIZABLE LIPIDS BRISTOL-MYERS SQUIBB COMPANY (US) 2024-11-28 WO disclosed
EP-3720431-B1 FATTY ACID DERIVATIVES FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS BASF AS (NO) 2024-10-30 EP disclosed
US-20240156769-A1 FATTY ACID DERIVATIVES FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS BASF AS (NO) 2024-05-16 US disclosed
WO-2024073626-A2 ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS NUVATION BIO INC. (US) 2024-04-04 WO disclosed
US-11925614-B2 Fatty acid derivatives for treating non-alcoholic steatohepatitis BASF AS (NO) 2024-03-12 US disclosed
US-20210177794-A1 FATTY ACID DERIVATIVES FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS BASF AS (NO) 2021-06-17 US disclosed
US-11014871-B2 “Multi-target” compounds with inhibitory activity towards histone deacetylases and tubulin polymerisation, for use in the treatment of cancer CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2021-05-25 US disclosed
EP-3720431-A1 FATTY ACID DERIVATIVES FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS BASF AS (NO) 2020-10-14 EP disclosed
CN-111712240-A Fatty acid derivatives for the treatment of non-alcoholic steatohepatitis 巴斯夫股份公司 2020-09-25 CN disclosed
WO-2020191261-A1 INDAZOLES AS LRRK2 INHIBITORS E-SCAPE BIO, INC. (US) 2020-09-24 WO disclosed
WO-2020191261-A1 INDAZOLES AS LRRK2 INHIBITORS E-SCAPE BIO, INC. (US) 2020-09-24 WO disclosed
WO-2019111048-A1 FATTY ACID DERIVATIVES FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS BASF AS (NO) 2019-06-13 WO disclosed
US-20190023645-A1 \"MULTI-TARGET\" COMPOUNDS WITH INHIBITORY ACTIVITY TOWARDS HISTONE DEACETYLASES AND TUBULIN POLYMERISATION, FOR USE IN THE TREATMENT OF CANCER UNIVERSITE PARIS-SUD (FR) 2019-01-24 US disclosed
CN-103827272-A Low sulfur fuel compositions having improved lubricity BUTAMAX TM ADVANCED BIOFUELS 2014-05-28 CN disclosed
US-20080045596-A1 Ep2 Receptor Agonists ASTERAND, INC. 2008-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210177794-A1 FATTY ACID DERIVATIVES FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS CPT1A, NR1H3, NR1H2 CYP1A2 182/4885GAA 1055/4885MGAM 2940/4885
US-20240156769-A1 FATTY ACID DERIVATIVES FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS CPT1A, NR1H2, NR1H3 CYP1A2 178/4885GAA 1063/4885MGAM 2971/4885
US-20260102501-A1 ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS NR5A1, NR5A2, NR3C1 CYP1A2 2840/4885GAA 3633/4885MGAM 4547/4885
US-20190023645-A1 \"MULTI-TARGET\" COMPOUNDS WITH INHIBITORY ACTIVITY TOWARDS HISTONE DEACETYLASES AND TUBULIN POLYMERISATION, FOR USE IN THE TREATMENT OF CANCER HDAC6, HDAC1, HDAC5 CYP1A2 2883/4885GAA 291/4885MGAM 2538/4885
US-12440466-B2 Fatty acid derivatives for treating non-alcoholic steatohepatitis CPT1A, NR1H2, NR1H3 CYP1A2 178/4885GAA 1063/4885MGAM 2971/4885
US-11014871-B2 “Multi-target” compounds with inhibitory activity towards histone deacetylases and tubulin polymerisation, for use in the treatment of cancer HDAC6, HDAC1, HDAC5 CYP1A2 2916/4885GAA 447/4885MGAM 2736/4885
US-20080045596-A1 Ep2 Receptor Agonists PTGER2, PTGER1, PTGER3 CYP1A2 315/4885GAA 4742/4885MGAM 4254/4885
US-20240390284-A1 IONIZABLE LIPIDS NPC1L1, ABCB4, NPC1 CYP1A2 4833/4885GAA 660/4885MGAM 2770/4885
US-11925614-B2 Fatty acid derivatives for treating non-alcoholic steatohepatitis CPT1A, NR1H3, NR1H2 CYP1A2 182/4885GAA 1055/4885MGAM 2940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.