Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | RAF1 | P04049 | 3/20 | 0.37 |
| ▸ | BRAF | P15056 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.35 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28158713 | 0.75 | ACSS2 (0.39) | RAB9AMAPTALDH1A1HTTHDAC6 | |
| SCHEMBL209641 | 0.75 | KDM4E (0.46) | RAB9AMAPTALDH1A1HTTKDM4E | |
| SCHEMBL25080562 | 0.75 | NPC1 (0.44) | RAB9AMAPTALDH1A1HDAC6KDM4E | |
| SCHEMBL16042846 | 0.75 | MAPK1 (0.51) | RAB9AMAPTALDH1A1HTTHDAC6 | |
| Hydrochloric Acid SCHEMBL28501510 | 0.73 | KDM4E (0.43) | RAB9AMAPTALDH1A1HDAC6KDM4E | |
| SCHEMBL209281 | 0.72 | ALDH1A1 (0.54) | RAB9AMAPTALDH1A1HTTKDM4E | |
| SCHEMBL7850067 | 0.70 | RAB9A (0.62) | RAB9AMAPTALDH1A1HTTKDM4E | |
| SCHEMBL25080570 | 0.69 | ATM (0.54) | RAB9AMAPTALDH1A1HTTKDM4E | |
| Hydrochloric Acid SCHEMBL28428173 | 0.68 | RAB9A (0.61) | RAB9AMAPTALDH1A1HTTKDM4E | |
| SCHEMBL28156519 | 0.68 | ALDH1A1 (0.50) | RAB9AMAPTALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338959-B2 | Diamino-pyrimidines and their use as angiogenesis inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2008-03-04 | — | — | US | disclosed |