Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14274283 | 0.75 | RAB9A (0.44) | ALDH1A1MAPTRAB9AHTTHPGD | |
| SCHEMBL3370266 | 0.75 | HCAR3 (0.50) | ACSS2RAB9AHTTHPGDKDM4E | |
| SCHEMBL2362373 | 0.74 | CNR2 (0.44) | ACSS2CNR2KDM4ECYP1A2MEN1 | |
| SCHEMBL16736782 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAPTRAB9AHTTKDM4E | |
| SCHEMBL8799913 | 0.72 | SMN1; SMN2 (0.60) | ACSS2ALDH1A1MAPTRAB9AHTT | |
| SCHEMBL20495470 | 0.72 | FAAH (0.39) | ACSS2CA12CA9CA1CA2 | |
| SCHEMBL2362098 | 0.71 | KDM4E (0.55) | ACSS2ALDH1A1MAPTRAB9AHTT | |
| SCHEMBL15111050 | 0.67 | MAPT (0.44) | ACSS2ALDH1A1MAPTRAB9AHTT | |
| SCHEMBL28156519 | 0.66 | ALDH1A1 (0.50) | ALDH1A1MAPTRAB9AHTTHPGD | |
| SCHEMBL28141945 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106983751-A | Two ring substituted uracils and application thereof | 拜耳医药股份有限公司 | 2017-07-28 | — | — | CN | disclosed |