Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 7/20 | 0.50 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.50 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 8/20 | 0.37 |
| ▸ | HTR2A | P28223 | 8/20 | 0.37 |
| ▸ | DRD3 | P35462 | 8/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677973 | 0.75 | DRD2 (0.49) | SLC9A1SLC9A5SLC9A2MTNR1BDRD2 | |
| SCHEMBL8489075 | 0.75 | MTNR1B (0.56) | SLC9A1SLC9A5SLC9A2MTNR1BKIF11 | |
| Methylamine SCHEMBL22076722 | 0.74 | SLC9A1 (0.53) | SLC9A1SLC9A5SLC9A2MTNR1BKIF11 | |
| SCHEMBL19690310 | 0.74 | SLC9A1 (0.46) | SLC9A1SLC9A5SLC9A2MTNR1BKIF11 | |
| SCHEMBL19699408 | 0.74 | SLC9A1 (0.46) | SLC9A1SLC9A5SLC9A2MTNR1BKIF11 | |
| SCHEMBL17781855 | 0.74 | SLC9A1 (0.46) | SLC9A1SLC9A5SLC9A2MTNR1BKIF11 | |
| SCHEMBL14276382 | 0.73 | SLC9A1 (0.70) | SLC9A1SLC9A5SLC9A2MTNR1BDRD2 | |
| SCHEMBL14276381 | 0.72 | SLC9A1 (0.64) | SLC9A1SLC9A5SLC9A2MTNR1BDRD2 | |
| SCHEMBL8489071 | 0.71 | SLC9A1 (0.53) | SLC9A1SLC9A5SLC9A2MTNR1BKIF11 | |
| SCHEMBL19226925 | 0.71 | MTNR1B (0.66) | SLC9A1SLC9A5SLC9A2MTNR1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326705-B2 | Heterocyclic sodium/proton exchange inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-05 | — | — | US | disclosed |