Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.36 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13890679 | 0.75 | SCN4A (0.32) | RAPGEF4 | |
| SCHEMBL28951 | 0.73 | RAPGEF4 (0.59) | RAPGEF4ACHEKDM4EALDH1A1LMNA | |
| SCHEMBL1551822 | 0.73 | RAPGEF4 (0.59) | RAPGEF4ACHEKDM4EALDH1A1LMNA | |
| SCHEMBL13083356 | 0.72 | ACHE (0.43) | RAPGEF4ACHEALDH1A1LMNAMAPT | |
| SCHEMBL5180888 | 0.70 | RAPGEF4 (0.56) | RAPGEF4ACHEKDM4EALDH1A1LMNA | |
| SCHEMBL28482658 | 0.70 | RAPGEF4 (0.56) | RAPGEF4ACHEKDM4EALDH1A1LMNA | |
| SCHEMBL10412763 | 0.70 | RAPGEF4 (0.56) | RAPGEF4ACHEKDM4EALDH1A1LMNA | |
| SCHEMBL13410909 | 0.69 | RAPGEF4 (0.41) | RAPGEF4ACHEKDM4EALDH1A1LMNA | |
| SCHEMBL13366299 | 0.68 | TDP1 (0.44) | RAPGEF4ACHEALDH1A1CYP1A2CYP2A6 | |
| SCHEMBL6255294 | 0.67 | RAPGEF4 (0.53) | RAPGEF4ACHEKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4098685-A1 | CROSSLINKED OLEFINIC THERMOPLASTIC ELASTOMER FOAMED PARTICLES AND METHOD FOR PRODUCING SAME | JSP Corporation (JP) | 2022-12-07 | — | — | EP | disclosed |
| US-11383008-B2 | Surface-modified polymeric substrates grafted with a properties-imparting compound using clip chemistry | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2022-07-12 | — | — | US | disclosed |
| US-20190247551-A1 | SURFACE-MODIFIED POLYMERIC SUBSTRATES GRAFTED WITH A PROPERTIES-IMPARTING COMPOUND USING CLIP CHEMISTRY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2019-08-15 | — | — | US | disclosed |
| EP-1467997-B1 | PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP | TAISHO PHARMACEUTICAL CO LTD (JP) | 2008-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190247551-A1 | SURFACE-MODIFIED POLYMERIC SUBSTRATES GRAFTED WITH A PROPERTIES-IMPARTING COMPOUND USING CLIP CHEMISTRY | CLASP1, MACF1, MICA | RAPGEF4 2826/4885UGT2B17 2169/4885ACHE 3204/4885 |
| US-11383008-B2 | Surface-modified polymeric substrates grafted with a properties-imparting compound using clip chemistry | CLASP1, MACF1, MICA | RAPGEF4 2826/4885UGT2B17 2169/4885ACHE 3204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.