Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 13/20 | 0.57 |
| ▸ | CES1 | P23141 | 7/20 | 0.55 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | PLA2G4C | Q9UP65 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334204 | 0.78 | ALDH1A1 (0.62) | FAAHMEN1CYP1A2KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL28627218 | 0.76 | ALDH1A1 (0.61) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL466531 | 0.76 | ALDH1A1 (0.85) | MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL809819 | 0.75 | FAAH (0.86) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL14770949 | 0.74 | FAAH (0.56) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL463411 | 0.73 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL13857653 | 0.73 | ALDH1A1 (0.56) | CES2ALDH1A1 | |
| SCHEMBL20032050 | 0.73 | ALDH1A1 (0.37) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL13090411 | 0.72 | ALDH1A1 (0.55) | ALDH1A1 | |
| SCHEMBL2819894 | 0.71 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1900732-A1 | NOVEL NITROGENATED HETEROCYCLIC COMPOUND AND SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2008-03-19 | — | — | EP | disclosed |