Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | ESRRA | P11474 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280256 | 0.84 | VCAM1 (0.41) | VCAM1MAPTRAD51KMT2AKAT2B | |
| SCHEMBL14280268 | 0.84 | KMT2A (0.44) | MAPTKMT2ARAB9AMAPK1TDP1 | |
| SCHEMBL14280242 | 0.84 | ALDH1A1 (0.40) | MAPTKMT2AMAPK1TDP1NPC1 | |
| SCHEMBL14306621 | 0.83 | ALDH1A1 (0.36) | MAPTKMT2AMAPK1TDP1NPC1 | |
| SCHEMBL14280240 | 0.80 | SMN1; SMN2 (0.41) | MAPTKMT2ARAB9ANPC1MEN1 | |
| SCHEMBL14280244 | 0.78 | CYP19A1 (0.36) | KMT2ANPC1ATMGPR35 | |
| SCHEMBL14306623 | 0.78 | VCAM1 (0.41) | VCAM1MAPTRAD51KMT2AKAT2B | |
| SCHEMBL13580425 | 0.77 | PTPRC (0.40) | MAPTKMT2AMAPK1TDP1NPC1 | |
| SCHEMBL13580331 | 0.75 | KMT2A (0.34) | MAPTKMT2ARAB9AMAPK1NPC1 | |
| SCHEMBL18877782 | 0.72 | BRD4 (0.34) | KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314692-B2 | Phenylazomethylene-cyclohexadienone derivatives comprising electron withdrawing group and electrophotographic photoreceptor comprising the derivatives | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-01-01 | — | — | US | disclosed |