Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.48 |
| ▸ | MET | P08581 | 7/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13599036 | 0.89 | HTR7 (0.45) | HTR6METHTR7HTR2CCYP3A4 | |
| SCHEMBL14468673 | 0.76 | DYRK1A (0.50) | HTR6METHTR7HTR2CCYP3A4 | |
| SCHEMBL20007689 | 0.74 | HTR7 (0.46) | HTR6METHTR7HTR2CCYP3A4 | |
| SCHEMBL344080 | 0.72 | MET (0.52) | HTR6METHTR7HTR2CCYP3A4 | |
| SCHEMBL3145297 | 0.71 | HTR6 (0.56) | HTR6 | |
| SCHEMBL3148459 | 0.70 | HTR6 (0.48) | HTR6HTR7 | |
| SCHEMBL3935685 | 0.69 | MET (0.46) | HTR6METHTR7HTR2CCYP3A4 | |
| SCHEMBL28777419 | 0.69 | HTR7 (0.40) | HTR6METHTR7HTR2CCYP3A4 | |
| SCHEMBL13303274 | 0.66 | HTR6 (0.67) | HTR6 | |
| SCHEMBL13325665 | 0.65 | HTR6 (0.71) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008025857-A2 | NEW METHOD FOR THE TREATMENT OF INFLAMMATORY DISEASES | TOPOTARGET SWITZERLAND SA (CH) | 2008-03-06 | — | — | WO | disclosed |