SCHEMBL14280392

SCHEMBL14280392

CCCCn1c2ccc(C)cc2c(=O)c2cc(OC)ccc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.59
HSD17B10 Q99714 1/20 0.59
PGR P06401 3/20 0.55
RORA P35398 3/20 0.55
RORC P51449 3/20 0.55
RORB Q92753 3/20 0.55
PLA2G2A P14555 2/20 0.51
MARK4 Q96L34 1/20 0.48
MAOA P21397 2/20 0.48
MAOB P27338 2/20 0.48
TSHR P16473 1/20 0.46
MAPK1 P28482 1/20 0.46
KMT2A Q03164 1/20 0.46
DYRK1A Q13627 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
CNR2 P34972 2/20 0.46
CNR1 P21554 1/20 0.44
PTGER4 P35408 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14160805 0.93 KDM4E (0.62) KDM4EHSD17B10PGRRORARORC
SCHEMBL14160813 0.88 KDM4E (0.57) KDM4EHSD17B10PGRRORARORC
SCHEMBL29717634 0.87 KDM4E (0.56) KDM4EHSD17B10PGRRORARORC
SCHEMBL30213498 0.87 KDM4E (0.56) KDM4EHSD17B10PGRRORARORC
SCHEMBL12611201 0.87 KDM4E (0.56) KDM4EHSD17B10PGRRORARORC
SCHEMBL17190827 0.86 RORA (0.63) PGRRORARORCRORBMARK4
SCHEMBL13471984 0.83 RORA (0.59) PGRRORARORCRORBCNR2
SCHEMBL14160802 0.83 KDM4E (0.51) KDM4EHSD17B10PGRRORARORC
SCHEMBL8085590 0.82 PGR (0.71) PGRRORARORCRORBMARK4
SCHEMBL14160816 0.82 DYRK1A (0.57) KDM4EHSD17B10PGRRORARORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080020323-A1 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2008-01-24 US disclosed
US-20080020323-A1 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2008-01-24 US disclosed