SCHEMBL8085590

SCHEMBL8085590

CCCCn1c2ccccc2c(=O)c2cc(C)ccc21

nearest known ligand 0.71

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.71
RORA P35398 2/20 0.71
RORC P51449 2/20 0.71
RORB Q92753 2/20 0.71
SMN1; SMN2 Q16637 4/20 0.58
MAPT P10636 4/20 0.58
RXFP1 Q9HBX9 2/20 0.58
THRB P10828 1/20 0.58
TP53 P04637 3/20 0.56
MARK4 Q96L34 2/20 0.55
ALDH1A1 P00352 2/20 0.55
CSF1R P07333 1/20 0.54
SLC6A4 P31645 2/20 0.53
SLC6A2 P23975 1/20 0.53
HRH1 P35367 1/20 0.53
ABCB1 P08183 1/20 0.53
P2RX4 Q99571 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14280390 0.91 PGR (0.63) PGRRORARORCRORBSMN1; SMN2
SCHEMBL17190827 0.90 RORA (0.63) PGRRORARORCRORBSMN1; SMN2
SCHEMBL29654225 0.88 RORA (0.62) PGRRORARORCRORBSMN1; SMN2
SCHEMBL14947364 0.88 PGR (0.74) PGRRORARORCRORBALDH1A1
SCHEMBL14493936 0.88 RORA (0.62) PGRRORARORCRORBSMN1; SMN2
SCHEMBL10730998 0.88 PGR (0.70) PGRRORARORCRORBALDH1A1
SCHEMBL13471984 0.87 RORA (0.59) PGRRORARORCRORBSMN1; SMN2
SCHEMBL14280386 0.86 PGR (0.56) PGRRORARORCRORBSMN1; SMN2
SCHEMBL29543602 0.84 RORA (0.55) PGRRORARORCRORBMAPT
SCHEMBL8086740 0.84 RORA (0.55) PGRRORARORCRORBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120045616-A1 POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR FORMING CURED FILM, CURED FILM, ORGANIC EL DISPLAY DEVICE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-02-23 US disclosed
US-20110121280-A1 SUBSTRATE, CONDUCTIVE PATTERN FORMATION PROCESS AND ORGANIC THIN FILM TRANSISTOR KONICA MINOLTA HOLDINGS, INC. (JP) 2011-05-26 US disclosed
US-20110121280-A1 SUBSTRATE, CONDUCTIVE PATTERN FORMATION PROCESS AND ORGANIC THIN FILM TRANSISTOR KONICA MINOLTA HOLDINGS, INC. (JP) 2011-05-26 US disclosed
US-20080145785-A1 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-06-19 US disclosed
US-20080145785-A1 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-06-19 US disclosed
US-20080020323-A1 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2008-01-24 US disclosed
US-20080020323-A1 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2008-01-24 US disclosed
US-6054501-A CURABILITY; GLOSSINESS; CAN BE BLENDED WITH INKS, PAINTS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2000-04-25 US disclosed
EP-0844255-A1 PHOTOPOLYMERIZATION INITIATOR AND ACTINIC RADIATION-CURABLE COMPOSITION COMPRISING THE SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1998-05-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120045616-A1 POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR FORMING CURED FILM, CURED FILM, ORGANIC EL DISPLAY DEVICE AND LIQUID CRYSTAL DISPLAY DEVICE PELP1, EED, ARCN1 PGR 938/4885RORA 2350/4885RORC 3087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.