SCHEMBL17190827

SCHEMBL17190827

CCCCn1c2ccc(C)cc2c(=O)c2cc3c(cc21)c(=O)c1cc(C)ccc1n3CCCC

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RORA P35398 5/20 0.63
RORC P51449 5/20 0.63
RORB Q92753 5/20 0.63
PGR P06401 5/20 0.63
CSF1R P07333 1/20 0.51
SMN1; SMN2 Q16637 3/20 0.47
MAPT P10636 3/20 0.47
RXFP1 Q9HBX9 2/20 0.47
THRB P10828 1/20 0.47
TP53 P04637 2/20 0.46
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
KMT2A Q03164 1/20 0.44
TLR8 Q9NR97 1/20 0.43
MARK4 Q96L34 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16786336 0.94 RORA (0.57) RORARORCRORBPGRCSF1R
SCHEMBL13471984 0.91 RORA (0.59) RORARORCRORBPGRCSF1R
SCHEMBL8085590 0.90 PGR (0.71) RORARORCRORBPGRCSF1R
SCHEMBL20094723 0.89 RORA (0.52) RORARORCRORBPGRCSF1R
SCHEMBL12374352 0.87 RORA (0.69) RORARORCRORBPGRSMN1; SMN2
SCHEMBL14280392 0.86 KDM4E (0.59) RORARORCRORBPGRSMN1; SMN2
SCHEMBL13125230 0.84 RORA (0.58) RORARORCRORBPGRTLR8
SCHEMBL14280390 0.84 PGR (0.63) RORARORCRORBPGRCSF1R
SCHEMBL19885203 0.83 ALDH1A1 (0.48) RORARORCRORBPGRSMN1; SMN2
SCHEMBL14493936 0.83 RORA (0.62) RORARORCRORBPGRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180053907-A1 Quantum Dot Light-Emitting Device, Fabricating Method Thereof, Display Substrate and Display Apparatus BOE TECHNOLOGY GROUP CO., LTD. (CN) 2018-02-22 US disclosed
US-20180053907-A1 Quantum Dot Light-Emitting Device, Fabricating Method Thereof, Display Substrate and Display Apparatus BOE TECHNOLOGY GROUP CO., LTD. (CN) 2018-02-22 US disclosed
US-9884877-B2 Compound and organic photoelectronic device and image sensor SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-02-06 US disclosed
US-9884877-B2 Compound and organic photoelectronic device and image sensor SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-02-06 US disclosed
US-20150303378-A1 COMPOUND AND ORGANIC PHOTOELECTRONIC DEVICE AND IMAGE SENSOR SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-22 US disclosed
US-20150303378-A1 COMPOUND AND ORGANIC PHOTOELECTRONIC DEVICE AND IMAGE SENSOR SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-22 US disclosed