Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575282 | 0.88 | SOS1 (0.55) | MRGPRX1PTGS1PTGS2CYP19A1CYP1A2 | |
| SCHEMBL4575511 | 0.88 | PTGS1 (0.57) | MRGPRX1PTGS1PTGS2CYP19A1CYP1A2 | |
| SCHEMBL8099526 | 0.84 | CYP19A1 (0.42) | MRGPRX1PTGS1PTGS2CYP19A1CYP1A2 | |
| SCHEMBL14564503 | 0.79 | CYP19A1 (0.79) | PTGS1PTGS2CYP19A1CYP1A2CYP2C9 | |
| SCHEMBL8091827 | 0.79 | CA1 (0.38) | MRGPRX1PTGS1PTGS2CYP19A1CYP1A2 | |
| SCHEMBL13524349 | 0.77 | PTGS1 (0.65) | MRGPRX1PTGS1PTGS2CYP19A1CYP1A2 | |
| SCHEMBL31090806 | 0.77 | PTGS2 (0.50) | MRGPRX1PTGS1PTGS2CYP19A1CYP1A2 | |
| SCHEMBL8101831 | 0.76 | MAPK1 (0.46) | PTGS1PTGS2CYP19A1CYP1A2CYP2C9 | |
| SCHEMBL8107162 | 0.75 | PTGS1 (0.61) | PTGS1PTGS2CYP19A1CYP2C9LMNA | |
| SCHEMBL8107798 | 0.75 | PTGS2 (0.56) | PTGS1PTGS2CYP19A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080027011-A1 | Homogeneous paste and gel formulations | MERIAL LIMITED | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027011-A1 | Homogeneous paste and gel formulations | EPX, CAT, PEF1 | MRGPRX1 3080/4885PTGS1 101/4885PTGS2 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.