Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14278140 | 0.89 | PTGS2 (0.60) | PTGS2PTGS1ABCB11ALDH1A1CYP2C9 | |
| SCHEMBL14562085 | 0.83 | KDM4C (0.42) | PTGS2PTGS1ABCB11PDPK1CYP2C9 | |
| SCHEMBL13627353 | 0.83 | PTGS2 (0.66) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL14562086 | 0.82 | SMPD1 (0.43) | PTGS2PTGS1ABCB11PDPK1CYP2C9 | |
| SCHEMBL13197381 | 0.82 | PTGS2 (0.61) | PTGS2PTGS1ABCB11PDPK1CYP2C9 | |
| SCHEMBL8286994 | 0.80 | PTGS2 (0.71) | PTGS2PTGS1ABCB11ALDH1A1PDPK1 | |
| SCHEMBL14562021 | 0.80 | CA9 (0.60) | PTGS2CA1CA2CA9 | |
| SCHEMBL14562025 | 0.80 | PTGS2 (0.60) | PTGS2PTGS1ABCB11PDPK1CYP2C9 | |
| SCHEMBL14562034 | 0.80 | PTGS2 (0.40) | PTGS2PTGS1ABCB11PDPK1CYP2C9 | |
| SCHEMBL861691 | 0.79 | SMN1; SMN2 (0.64) | CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080027011-A1 | Homogeneous paste and gel formulations | MERIAL LIMITED | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027011-A1 | Homogeneous paste and gel formulations | EPX, CAT, PEF1 | PTGS2 329/4885PTGS1 101/4885ABCB11 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.