Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 12/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325061 | 0.88 | PTGS2 (0.71) | PTGS2PTGS1ALDH1A1ABCB11SMN1; SMN2 | |
| SCHEMBL14280460 | 0.83 | PTGS2 (0.60) | PTGS2PTGS1ALDH1A1ABCB11 | |
| SCHEMBL5698611 | 0.82 | PTGS2 (0.72) | PTGS2PTGS1ALDH1A1ABCB11SMN1; SMN2 | |
| SCHEMBL8639053 | 0.82 | PTGS2 (0.71) | PTGS2PTGS1ALDH1A1ABCB11SMN1; SMN2 | |
| SCHEMBL14278140 | 0.81 | PTGS2 (0.60) | PTGS2PTGS1ALDH1A1ABCB11SMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL27507738 | 0.81 | PTGS2 (0.70) | PTGS2PTGS1ALDH1A1ABCB11SMN1; SMN2 | |
| Deracoxib SCHEMBL24645 | 0.80 | PTGS2 (1.00) | PTGS2PTGS1ALDH1A1ABCB11 | |
| Deracoxib SCHEMBL29593653 | 0.80 | PTGS2 (1.00) | PTGS2PTGS1ALDH1A1ABCB11 | |
| SCHEMBL8286969 | 0.80 | PTGS2 (0.71) | PTGS2PTGS1ALDH1A1ABCB11 | |
| Deracoxib SCHEMBL28723602 | 0.79 | PTGS2 (0.98) | PTGS2PTGS1ALDH1A1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622471-B2 | Pyrazole derivatives having a pyridazine and pyridine functionality | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-11-24 | — | — | US | disclosed |
| US-20090137600-A1 | Antiplatelet agent and process for producing the same | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-05-28 | — | — | US | disclosed |
| US-20080064682-A1 | Pyrazole Derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20070254881-A1 | Pyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-11-01 | — | — | US | disclosed |
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254881-A1 | Pyrazole Derivative | PTGER1, PTGS1, PTGER2 | PTGS2 4/4885PTGS1 2/4885ALDH1A1 111/4885 |
| US-20080064682-A1 | Pyrazole Derivatives | NAT1, AR, CBR3 | PTGS2 2158/4885PTGS1 1600/4885ALDH1A1 248/4885 |
| US-20070219210-A1 | Amidopyrazole Derivative | PTGER1, PTGS1, PTGER2 | PTGS2 4/4885PTGS1 2/4885ALDH1A1 171/4885 |
| US-20090137600-A1 | Antiplatelet agent and process for producing the same | PFKP, GP6, PF4 | PTGS2 34/4885PTGS1 25/4885ALDH1A1 573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.