Sugi Predict

Sugi Predict / Compounds / SCHEMBL1428059

SCHEMBL1428059

SCHEMBL1428059

Cc1ccc(Cl)nc1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ MEN1 O00255 3/20 0.41
▸ KMT2A Q03164 3/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ CTSA P10619 1/20 0.40
▸ NAPRT Q6XQN6 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ HCAR2 Q8TDS4 1/20 0.38
▸ MDM2 Q00987 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ KMO O15229 2/20 0.37
▸ PIN1 Q13526 2/20 0.37
▸ GABRP O00591 1/20 0.37
▸ GABRD O14764 1/20 0.37
▸ GABRA1 P14867 1/20 0.37
▸ GABRB1 P18505 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29439572 1.00 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A
SCHEMBL28078792 0.98 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A
SCHEMBL20209504 0.83 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A
SCHEMBL31559908 0.82 POLB (0.43) ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A
SCHEMBL22715879 0.82 POLB (0.43) ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A
Clopyralid SCHEMBL29371357 0.80 KMT2A (0.50) ALDH1A1SMN1; SMN2MEN1KMT2ACYP2C9
Clopyralid SCHEMBL8535196 0.80 KMT2A (0.50) ALDH1A1SMN1; SMN2MEN1KMT2ACYP2C9
Clopyralid SCHEMBL54779 0.80 KMT2A (0.50) ALDH1A1SMN1; SMN2MEN1KMT2ACYP2C9
Potassium Ion SCHEMBL15398567 0.80 CTSA (0.35) ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A
SCHEMBL11842980 0.80 ALDH1A1 (0.44) ALDH1A1MEN1KMT2ACTSAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617789-B2 Small molecular inhibitors of NF-κb inducing kinase JANSSEN PHARMACEUTICA NV (BE) 2026-05-05 — — US disclosed
US-20260076968-A1 AZA-QUINOLINE COMPOUNDS AND USES THEREOF NOVARTIS AG (CH) 2026-03-19 — — US disclosed
EP-4034535-B1 AZA-QUINOLINE COMPOUNDS AND USES THEREOF NOVARTIS AG (CH) 2026-03-04 — — EP disclosed
US-12544374-B2 AZA-quinoline compounds and uses thereof NOVARTIS AG (CH) 2026-02-10 — — US disclosed
US-20250326739-A1 CD38 MODULATORS AND USES THEREOF AEOVIAN PHARMACEUTICALS INC (US) 2025-10-23 — — US disclosed
EP-4532483-A1 CD38 MODULATORS AND USES THEREOF Aeovian Pharmaceuticals, Inc. (US) 2025-04-09 — — EP disclosed
WO-2025051157-A1 PYRIDINE-2(1H)-KETONE PRMT5-MTA INHIBITOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 赛诺哈勃药业（成都）有限公司 2025-03-13 — — WO disclosed
CN-115181062-B Preparation method of 6-chloro-3-methyl-2-pyridine carboxylic acid methyl ester 八叶草健康产业研究院(厦门)有限公司 2025-02-07 — — CN disclosed
CN-115785064-B Preparation of trisubstituted pyridine derivatives and use thereof as modulators of aromatic hydrocarbon receptors 成都奥睿药业有限公司 2024-12-06 — — CN disclosed
EP-4467199-A2 SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE JANSSEN Pharmaceutica NV (BE) 2024-11-27 — — EP disclosed
US-20080153850-A1 Adamantyl Derivates as P2x7 Receptor Antagonists ASTRAZENECA AB (SE) 2008-06-26 — — US disclosed
EP-0806414-B1 Intermediates for herbicidal carboxamide derivatives BASF AG (DE) 2002-06-12 — — EP disclosed
EP-1207154-A1 Herbicidal carboxamide derivatives BASF AKTIENGESELLSCHAFT (DE) 2002-05-22 — — EP disclosed
EP-0488474-B1 Herbicidal carboxamide derivatives BASF AG (DE) 2002-04-17 — — EP disclosed
EP-0447004-B1 Herbicidal carboxamide derivatives SHELL INT RESEARCH (NL) 1998-01-28 — — EP disclosed
EP-0806414-A1 Intermediates for herbicidal carboxamide derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1997-11-12 — — EP disclosed
US-5384305-A Plant growth regulators SHELL RESEARCH LIMITED (GB) 1995-01-24 — — US disclosed
US-5294597-A 2-((Halophenyl)amido-)m,6-((halophenyl)oxy-)pyridines SHELL RESEARCH LIMITED (GB) 1994-03-15 — — US disclosed
EP-0488474-A1 Herbicidal carboxamide derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-06-03 — — EP disclosed
EP-0447004-A2 Herbicidal carboxamide derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-09-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260076968-A1 AZA-QUINOLINE COMPOUNDS AND USES THEREOF EZH2, SUZ12, NR3C1 ALDH1A1 1941/4885SMN1; SMN2 492/4885MAPK1 1536/4885
US-20250326739-A1 CD38 MODULATORS AND USES THEREOF CD38, CD22, CD47 ALDH1A1 141/4885SMN1; SMN2 3861/4885MAPK1 1709/4885
US-12544374-B2 AZA-quinoline compounds and uses thereof EZH2, NR3C1, SUZ12 ALDH1A1 1524/4885SMN1; SMN2 1004/4885MAPK1 1734/4885
US-20080153850-A1 Adamantyl Derivates as P2x7 Receptor Antagonists ADORA1, P2RX1, P2RY1 ALDH1A1 744/4885SMN1; SMN2 3067/4885MAPK1 547/4885
US-12617789-B2 Small molecular inhibitors of NF-κb inducing kinase IRAK3, IKBKB, IKBKG ALDH1A1 3824/4885SMN1; SMN2 4444/4885MAPK1 54/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.