Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053624 | 1.00 | SIGMAR1 (0.48) | SIGMAR1KDM4EGAAALDH1A1KMT2A | |
| SCHEMBL5358995 | 0.85 | SIGMAR1 (0.46) | SIGMAR1ALDH1A1KMT2APOLBAGTR1 | |
| SCHEMBL5354574 | 0.85 | SIGMAR1 (0.46) | SIGMAR1ALDH1A1KMT2APOLBAGTR1 | |
| Hydrochloric Acid SCHEMBL6419075 | 0.82 | POLB (0.45) | SIGMAR1KDM4EALDH1A1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL5603768 | 0.82 | POLB (0.45) | SIGMAR1KDM4EALDH1A1KMT2APOLB | |
| SCHEMBL8091308 | 0.81 | MAPT (0.56) | SIGMAR1KDM4EGAAALDH1A1KMT2A | |
| SCHEMBL6054984 | 0.81 | MAPT (0.56) | SIGMAR1KDM4EGAAALDH1A1KMT2A | |
| SCHEMBL14280784 | 0.80 | CYP1A2 (0.38) | SIGMAR1KDM4EGAAALDH1A1KMT2A | |
| SCHEMBL5354775 | 0.78 | POLB (0.45) | SIGMAR1KDM4EALDH1A1KMT2APOLB | |
| SCHEMBL5354773 | 0.78 | POLB (0.45) | SIGMAR1KDM4EALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670434-B2 | Transition metal complex | SOLVAY POLYOLEFINS EUROPE-BELGIUM (SOCIETE ANONYME) (BE) | 2003-12-30 | — | — | US | disclosed |
| US-20030018147-A1 | Catalytic complexes and their use for polymerizing alpha-olefins | SOLVAY POLYOLEFINS EUROPE-BELGIUM (BE) | 2003-01-23 | — | — | US | disclosed |
| EP-1260515-A1 | Catalytic complexes and their use for polymerizing alpha-olefins | SOLVAY POLYOLEFINS EUROPE - BELGIUM (Société Anonyme) (BE) | 2002-11-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018147-A1 | Catalytic complexes and their use for polymerizing alpha-olefins | POLA1, ETFB, POLB | SIGMAR1 861/4885KDM4E 3162/4885GAA 1091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.