Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.52 |
| ▸ | CCR8 | P51685 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24729625 | 0.85 | CCR1 (0.68) | CCR1CCR8HTR7MEN1RAB9A | |
| SCHEMBL31655443 | 0.83 | CCR1 (0.46) | CCR1CCR8HTR7KDM4ELMNA | |
| SCHEMBL29899251 | 0.83 | NOS3 (0.54) | CCR1CCR8HTR7ALDH1A1CD44 | |
| SCHEMBL12999311 | 0.81 | HTR7 (0.44) | CCR1CCR8HTR7CYP2A6CYP1A2 | |
| SCHEMBL3623211 | 0.80 | CCR1 (0.42) | CCR1CCR8HTR7KDM4ELMNA | |
| SCHEMBL4401753 | 0.79 | CCR1 (0.52) | CCR1CCR8HTR7KDM4ELMNA | |
| SCHEMBL25999784 | 0.78 | NOS3 (0.48) | CCR1CCR8HTR7CYP2A6CYP1A2 | |
| SCHEMBL15570417 | 0.78 | AR (0.45) | CCR1CCR8HTR7LMNACCR5 | |
| SCHEMBL12999270 | 0.78 | DHFR (0.40) | HTR7KDM4ELMNATP53ALOX15 | |
| SCHEMBL18396906 | 0.78 | RAB9A (0.41) | CCR1CCR8HTR7LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021180-A1 | CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION | REPSOL QUIMICA, S.A. | 2008-01-24 | — | — | US | disclosed |
| US-20080021180-A1 | CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION | REPSOL QUIMICA, S.A. | 2008-01-24 | — | — | US | disclosed |