Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 9/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ARF6 | P62330 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886271 | 0.87 | ARF6 (0.43) | CNR1CNR2ARF6 | |
| SCHEMBL3551780 | 0.82 | MET (0.41) | CNR1ALDH1A1CNR2KDM4E | |
| SCHEMBL3557048 | 0.78 | ALOX5 (0.45) | CNR1ALDH1A1CNR2ARF6KDM4E | |
| SCHEMBL4872815 | 0.78 | CNR1 (0.43) | CNR1CNR2 | |
| SCHEMBL3552117 | 0.76 | CNR1 (0.43) | CNR1ALDH1A1CNR2KDM4E | |
| SCHEMBL3556439 | 0.75 | CNR1 (0.40) | CNR1CNR2ARF6 | |
| SCHEMBL3555218 | 0.73 | TP53 (0.45) | CNR1ALDH1A1CNR2SMN1; SMN2KDM4E | |
| SCHEMBL13593105 | 0.73 | MAT2A (0.41) | CNR1CNR2SMN1; SMN2KDM4E | |
| SCHEMBL5819094 | 0.72 | DPP4 (0.43) | CNR1ALDH1A1CNR2SMN1; SMN2KDM4E | |
| SCHEMBL4872806 | 0.72 | CNR1 (0.41) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317012-B2 | Bicyclic heterocycles as cannabinoind-1 receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-08 | — | — | US | disclosed |