Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.46 |
| ▸ | CD74 | P04233 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280876 | 0.83 | MIF (0.48) | MIFCD74NPC1MEN1KMT2A | |
| SCHEMBL14280873 | 0.82 | NPC1 (0.47) | MIFCD74NPC1MEN1KMT2A | |
| SCHEMBL28859246 | 0.71 | MIF (0.48) | MIFCD74NPC1ALDH1A1GSK3A | |
| SCHEMBL14280874 | 0.71 | MIF (0.43) | MIFCD74NPC1MEN1KMT2A | |
| SCHEMBL8730804 | 0.68 | MIF (0.50) | MIFCD74MEN1KMT2AALDH1A1 | |
| SCHEMBL1522614 | 0.67 | ALDH1A1 (0.57) | MIFCD74NPC1ALDH1A1MAPK1 | |
| SCHEMBL1522612 | 0.66 | MIF (0.55) | MIFCD74NPC1MEN1KMT2A | |
| SCHEMBL8725339 | 0.66 | FAAH (0.47) | MIFMEN1KMT2AALDH1A1IDO1 | |
| SCHEMBL10994602 | 0.65 | HPGD (0.58) | MIFCD74NPC1MEN1KMT2A | |
| SCHEMBL8730208 | 0.65 | IDO1 (0.59) | MIFCD74MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021079-A1 | Compounds, Compositions, and Methods | CYTOKINETICS, INC. | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021079-A1 | Compounds, Compositions, and Methods | ALPP, PCNA, MKI67 | MIF 4183/4885CD74 2220/4885NPC1 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.