Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.48 |
| ▸ | CD74 | P04233 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RGS4 | P49798 | 1/20 | 0.37 |
| ▸ | RGS8 | P57771 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29096381 | 0.74 | MAPK1 (0.38) | NPC1GSK3AGSK3BPOLBALDH1A1 | |
| SCHEMBL8730804 | 0.72 | MIF (0.50) | MIFCD74GSK3BIDO1POLB | |
| SCHEMBL14280875 | 0.71 | MIF (0.46) | MIFCD74NPC1GSK3AGSK3B | |
| SCHEMBL8730208 | 0.70 | IDO1 (0.59) | MIFCD74IDO1POLBALDH1A1 | |
| SCHEMBL1522612 | 0.68 | MIF (0.55) | MIFCD74NPC1GSK3AGSK3B | |
| SCHEMBL8725339 | 0.68 | FAAH (0.47) | MIFIDO1ALDH1A1 | |
| SCHEMBL9868147 | 0.66 | KDM4E (0.49) | GSK3AGSK3BPOLBALDH1A1LMNA | |
| SCHEMBL9868143 | 0.66 | L3MBTL1 (0.53) | GSK3AGSK3BPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL1522614 | 0.66 | ALDH1A1 (0.57) | MIFCD74NPC1ALDH1A1LMNA | |
| SCHEMBL9034591 | 0.66 | HPGD (0.37) | MIFIDO1ALDH1A1ASAH1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115043788-B | Trifluoromethyl oxazol-2-one compound and preparation method and application thereof | 南京工业大学 | 2023-10-20 | — | — | CN | disclosed |
| CN-115043788-A | Trifluoromethyl oxazole-2-ketone compound and preparation method and application thereof | 南京工业大学 | 2022-09-13 | — | — | CN | disclosed |