Sugi Predict

Sugi Predict / Compounds / SCHEMBL14280962

SCHEMBL14280962

SCHEMBL14280962

c1ccc(Oc2nc3c4nc(Oc5ccccc5)c(Oc5ccccc5)nc4c4nc(-c5ccccc5)c(-c5ccccc5)nc4c3nc2Oc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA2A P29274 1/20 0.54
▸ MAPT P10636 4/20 0.47
▸ ABCG2 Q9UNQ0 1/20 0.47
▸ ALDH1A1 P00352 6/20 0.44
▸ MEN1 O00255 6/20 0.44
▸ KMT2A Q03164 6/20 0.44
▸ L3MBTL1 Q9Y468 4/20 0.44
▸ CYP1A2 P05177 2/20 0.44
▸ CYP2C19 P33261 2/20 0.44
▸ CYP2C9 P11712 1/20 0.44
▸ LMNA P02545 5/20 0.42
▸ HTT P42858 4/20 0.42
▸ NPSR1 Q6W5P4 3/20 0.42
▸ GPR55 Q9Y2T6 2/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.42
▸ LTA4H P09960 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ TDP1 Q9NUW8 4/20 0.42
▸ KDM4E B2RXH2 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17445639 0.91 ADORA2A (0.47) ADORA2AMAPTABCG2ALDH1A1MEN1
SCHEMBL13197741 0.80 LMNA (0.54) ADORA2AMAPTALDH1A1MEN1KMT2A
SCHEMBL12340142 0.79 LTA4H (0.46) ADORA2AMAPTABCG2ALDH1A1MEN1
SCHEMBL14280969 0.79 LMNA (0.52) ADORA2AMAPTABCG2ALDH1A1KMT2A
SCHEMBL14280963 0.78 SMN1; SMN2 (0.59) ADORA2AMAPTALDH1A1MEN1KMT2A
SCHEMBL12340135 0.77 LTA4H (0.48) ADORA2AMAPTABCG2ALDH1A1KMT2A
SCHEMBL14316182 0.74 SMN1; SMN2 (0.49) ADORA2AMAPTABCG2ALDH1A1MEN1
SCHEMBL13197730 0.74 ADORA2A (0.42) ADORA2AMAPTABCG2ALDH1A1MEN1
SCHEMBL17445633 0.72 LMNA (0.53) MAPTABCG2ALDH1A1MEN1KMT2A
SCHEMBL17445628 0.72 SMN1; SMN2 (0.53) ADORA2AMAPTALDH1A1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2023-06-13 — — US disclosed
US-20210376247-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2021-12-02 — — US disclosed
US-11152574-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2021-10-19 — — US disclosed
US-11094888-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2021-08-17 — — US disclosed
US-20210083194-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2021-03-18 — — US disclosed
US-10263192-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2019-04-16 — — US disclosed
US-9960360-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 — — US disclosed
US-20180040828-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2018-02-08 — — US disclosed
US-20160020403-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-21 — — US disclosed
US-20080014464-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2008-01-17 — — US disclosed
US-20080014464-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2008-01-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11152574-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle RPL21, RPS21, AOC2 ADORA2A 1270/4885MAPT 4198/4885ABCG2 3743/4885
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle RPS17, RPS19, CDK17 ADORA2A 1825/4885MAPT 3852/4885ABCG2 3808/4885
US-20210083194-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE RPL21, RPS21, AOC2 ADORA2A 1270/4885MAPT 4198/4885ABCG2 3743/4885
US-11094888-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle SLC18A1, SLC18A2, AOC2 ADORA2A 674/4885MAPT 2683/4885ABCG2 936/4885
US-10263192-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle SLC18A1, SLC18A2, AOC2 ADORA2A 674/4885MAPT 2683/4885ABCG2 936/4885
US-20180040828-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE SLC18A1, SLC18A2, AOC2 ADORA2A 674/4885MAPT 2683/4885ABCG2 936/4885
US-20160020403-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE SLC18A1, SLC18A2, AOC2 ADORA2A 674/4885MAPT 2683/4885ABCG2 936/4885
US-20210376247-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE RPS17, RPS19, CDK17 ADORA2A 1825/4885MAPT 3852/4885ABCG2 3808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.