Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14221370 | 0.84 | ALDH1A1 (0.56) | CYP3A4RAB9ASMN1; SMN2KMT2ANPC1 | |
| SCHEMBL14282208 | 0.76 | RAB9A (0.53) | CYP3A4RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL14220831 | 0.75 | MCHR1 (0.59) | CYP3A4SMN1; SMN2LMNAKMT2APOLB | |
| SCHEMBL25968360 | 0.73 | EGLN2 (0.40) | CYP3A4LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL14282209 | 0.73 | NOTUM (0.54) | CYP3A4RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL14221276 | 0.73 | IDO1 (0.59) | CYP3A4RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL11049861 | 0.73 | ALDH1A1 (0.54) | CYP3A4RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL14282337 | 0.71 | NPBWR1 (0.46) | CYP3A4SMN1; SMN2LMNAKMT2APOLB | |
| SCHEMBL14282213 | 0.71 | CYP17A1 (0.56) | CYP3A4RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL14282211 | 0.71 | NPBWR1 (0.46) | CYP3A4RAB9ASMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320977-B2 | Fibrotic disorders; disorders characterized by harmful buildup of collagen and/or by excessive lysyl oxidase enzymatic activity | BAYER HEALTHCARE AG (DE) | 2008-01-22 | — | — | US | disclosed |