Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | CA6 | P23280 | 3/20 | 0.43 |
| ▸ | CA5A | P35218 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | MET | P08581 | 4/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14282669 | 0.92 | THRB (0.53) | THRBCA12CA4CA6CA5A | |
| SCHEMBL14282672 | 0.88 | THRB (0.46) | THRBCA12CA4CA6CA5A | |
| SCHEMBL14282673 | 0.88 | THRB (0.46) | THRBCA12CA4CA6CA5A | |
| SCHEMBL14282677 | 0.82 | THRB (0.49) | THRBALDH1A1MEN1LMNAMAPT | |
| SCHEMBL14282674 | 0.80 | ALDH1A1 (0.51) | THRBALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL28972692 | 0.79 | THRB (0.56) | THRBCA12CA4CA6CA5A | |
| SCHEMBL17036768 | 0.77 | THRB (0.71) | THRBCA12CA4CA6CA5A | |
| SCHEMBL14282668 | 0.77 | TP53 (0.41) | TP53TSHRHIF1AKDM4ESMN1; SMN2 | |
| SCHEMBL14282665 | 0.77 | PLK1 (0.44) | ALDH1A1MAPK1MEN1LMNAMAPT | |
| SCHEMBL14282666 | 0.76 | POLB (0.42) | ALDH1A1KDM4ELMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314654-B2 | Optically anisotropic element comprising discotic compound | FUJIFILM CORPORATION (JP) | 2008-01-01 | — | — | US | disclosed |
| US-7314654-B2 | Optically anisotropic element comprising discotic compound | FUJIFILM CORPORATION (JP) | 2008-01-01 | — | — | US | disclosed |