Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 4/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14282668 | 0.87 | TP53 (0.41) | SMN1; SMN2 | |
| SCHEMBL14282665 | 0.87 | PLK1 (0.44) | ALDH1A1LMNAL3MBTL1NPC1MAPT | |
| SCHEMBL14282666 | 0.87 | POLB (0.42) | ALDH1A1LMNANPC1MAPTRAB9A | |
| SCHEMBL14282667 | 0.84 | TP53 (0.48) | LMNANPC1SMN1; SMN2 | |
| SCHEMBL14282676 | 0.82 | THRB (0.44) | THRBALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL14415091 | 0.78 | THRB (0.45) | THRBALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL14318647 | 0.78 | AKR1C3 (0.39) | LMNAMAPTKMT2APPARAPPARG | |
| SCHEMBL14318648 | 0.77 | ADRB2 (0.35) | ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14282674 | 0.77 | ALDH1A1 (0.51) | THRBALDH1A1L3MBTL1NPC1MAPT | |
| SCHEMBL20024427 | 0.75 | THRB (0.49) | THRBALDH1A1LMNAL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314654-B2 | Optically anisotropic element comprising discotic compound | FUJIFILM CORPORATION (JP) | 2008-01-01 | — | — | US | disclosed |
| US-7314654-B2 | Optically anisotropic element comprising discotic compound | FUJIFILM CORPORATION (JP) | 2008-01-01 | — | — | US | disclosed |