Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14282668 | 0.95 | TP53 (0.41) | ABCG2CYP1A2 | |
| SCHEMBL14282667 | 0.91 | TP53 (0.48) | LMNANPC1 | |
| SCHEMBL14282666 | 0.89 | POLB (0.42) | PLK1LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL14282677 | 0.87 | THRB (0.49) | PLK1L3MBTL1LMNAALDH1A1MAPT | |
| SCHEMBL14282674 | 0.84 | ALDH1A1 (0.51) | L3MBTL1ALDH1A1MAPTHTTNPC1 | |
| SCHEMBL14282672 | 0.81 | THRB (0.46) | L3MBTL1ALDH1A1HTT | |
| SCHEMBL14282673 | 0.81 | THRB (0.46) | L3MBTL1ALDH1A1MAPTHTT | |
| SCHEMBL14318647 | 0.80 | AKR1C3 (0.39) | PLK1LMNAGAAMAPTKMT2A | |
| SCHEMBL14318648 | 0.79 | ADRB2 (0.35) | ALDH1A1ABCG2KMT2AMEN1LTA4H | |
| SCHEMBL14282676 | 0.77 | THRB (0.44) | LMNAALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314654-B2 | Optically anisotropic element comprising discotic compound | FUJIFILM CORPORATION (JP) | 2008-01-01 | — | — | US | disclosed |