Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.54 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12123733 | 0.88 | PRCP (0.55) | PRCPBACE1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL4695183 | 0.85 | PRCP (0.52) | PRCPBACE1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL4253158 | 0.85 | PRCP (0.55) | PRCPBACE1KDM4EKDM1ACARM1 | |
| SCHEMBL3662230 | 0.84 | BACE1 (0.58) | BACE1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14282940 | 0.84 | ALDH1A1 (0.52) | PRCPKDM4ELMNA | |
| SCHEMBL7280401 | 0.83 | SLC18A3 (0.58) | BACE1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4072745 | 0.82 | PRCP (0.49) | PRCPBACE1KDM4ECYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL11794123 | 0.81 | ADRA1D (0.60) | CYP2D6HTR2AHTR2CLMNASIGMAR1 | |
| SCHEMBL14198387 | 0.81 | DRD2 (0.60) | BACE1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8054450 | 0.80 | HTR2A (0.51) | BACE1KDM4ECYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317026-B2 | Sleep disorders; side effect reduction ; antihistamine antagonist | HYPNION, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-7317026-B2 | Sleep disorders; side effect reduction ; antihistamine antagonist | HYPNION, INC. (US) | 2008-01-08 | — | — | US | disclosed |