Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14282965 | 0.79 | NPC1 (0.56) | ALDH1A1KMT2AMEN1CHRM5CHRM3 | |
| SCHEMBL4257154 | 0.77 | SETD7 (0.56) | ALDH1A1DRD4LMNACHRM3 | |
| SCHEMBL6865166 | 0.76 | SIGMAR1 (0.67) | ALDH1A1KMT2ASIGMAR1MEN1GAA | |
| SCHEMBL18838272 | 0.76 | KMT2A (0.56) | ALDH1A1KMT2ADRD4DRD3LMNA | |
| SCHEMBL11036336 | 0.75 | SETD7 (0.53) | ALDH1A1DRD4 | |
| SCHEMBL7438034 | 0.75 | SIGMAR1 (0.65) | ALDH1A1KMT2ADRD4DRD3LMNA | |
| SCHEMBL7436834 | 0.75 | SIGMAR1 (0.65) | ALDH1A1KMT2ADRD4DRD3LMNA | |
| SCHEMBL4501570 | 0.73 | ALDH1A1 (0.56) | ALDH1A1KMT2ADRD4DRD3SIGMAR1 | |
| SCHEMBL4494539 | 0.72 | ALDH1A1 (0.57) | ALDH1A1DRD4LMNATSHRSIGMAR1 | |
| SCHEMBL6479844 | 0.72 | SIGMAR1 (0.75) | ALDH1A1KMT2ADRD4DRD3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317026-B2 | Sleep disorders; side effect reduction ; antihistamine antagonist | HYPNION, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-7317026-B2 | Sleep disorders; side effect reduction ; antihistamine antagonist | HYPNION, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-7189757-B2 | Treatment of sleep disorders using CNS target modulators | HYPNION, INC. (US) | 2007-03-13 | — | — | US | disclosed |
| US-7189757-B2 | Treatment of sleep disorders using CNS target modulators | HYPNION, INC. (US) | 2007-03-13 | — | — | US | disclosed |