Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6424876 | 0.94 | MAOB (0.42) | MAOBPPARGSMN1; SMN2FNTAFNTB | |
| SCHEMBL722684 | 0.81 | IDO1 (0.56) | MAOBIDO1AGXT | |
| SCHEMBL9849151 | 0.81 | GABRG2 (0.41) | MAOBIDO1AGXTSMN1; SMN2KDM4E | |
| SCHEMBL481257 | 0.77 | IDO1 (0.50) | MAOBIDO1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6156781 | 0.77 | CHRNA7 (0.43) | MAOBIDO1AGXTPPARGALDH1A1 | |
| SCHEMBL6420311 | 0.77 | APP (0.47) | IDO1PPARG | |
| SCHEMBL3825220 | 0.77 | CYP2A6 (0.37) | MAOBIDO1AGXTKDM4EALDH1A1 | |
| SCHEMBL4496052 | 0.76 | PREP (0.48) | IDO1AGXT | |
| SCHEMBL1539288 | 0.75 | MAOB (0.50) | MAOBSMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL1284441 | 0.74 | RAB9A (0.48) | MAOBSMN1; SMN2KDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8352193-B2 | Methods for deriving a cumulative ranking | TARGET DISCOVERY, INC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-7316931-B2 | Mass defect labeling for the determination of oligomer sequences | TARGET DISCOVERY, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-20070154900-A1 | Methods for determining protein and peptide terminal sequences | TARGET DISCOVERY, INC (US) | 2007-07-05 | — | — | US | disclosed |