Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 15/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3012099 | 0.92 | CYP3A4 (0.50) | APPCYP3A4IDO1 | |
| SCHEMBL6419484 | 0.84 | PCNA (0.37) | APP | |
| SCHEMBL4496052 | 0.80 | PREP (0.48) | APPIDO1RXRARXRBPREP | |
| SCHEMBL3426875 | 0.78 | AGXT (0.32) | APPCYP3A4IDO1 | |
| SCHEMBL14282994 | 0.77 | MAOB (0.47) | IDO1PPARG | |
| SCHEMBL9366384 | 0.76 | APP (0.40) | APPRXRARXRB | |
| SCHEMBL12855670 | 0.75 | AGXT (0.52) | IDO1 | |
| SCHEMBL906834 | 0.75 | IDO1 (0.48) | CYP3A4IDO1 | |
| SCHEMBL15489965 | 0.75 | TDP1 (0.37) | RXRARXRB | |
| SCHEMBL4050106 | 0.75 | APP (0.35) | APPCYP3A4IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8352193-B2 | Methods for deriving a cumulative ranking | TARGET DISCOVERY, INC. (US) | 2013-01-08 | — | — | US | disclosed |
| EP-2479578-A1 | Mass defect labeling for the determination of oligomer sequences | Target Discovery, Inc. (US) | 2012-07-25 | — | — | EP | disclosed |
| US-7316931-B2 | Mass defect labeling for the determination of oligomer sequences | TARGET DISCOVERY, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-20070154900-A1 | Methods for determining protein and peptide terminal sequences | TARGET DISCOVERY, INC (US) | 2007-07-05 | — | — | US | disclosed |
| US-6962818-B2 | Mass defect labeling for the determination of oligomer sequences | TARGET DISCOVERY (US) | 2005-11-08 | — | — | US | disclosed |