Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 6/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | AGXT | P21549 | 4/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12002628 | 0.85 | IDO1 (0.46) | MAOBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL722684 | 0.83 | IDO1 (0.56) | MAOBIDO1AGXT | |
| SCHEMBL9293349 | 0.81 | PGR (0.36) | MAOBIDO1AGXT | |
| SCHEMBL14282994 | 0.81 | MAOB (0.47) | MAOBSMN1; SMN2KDM4EIDO1AGXT | |
| SCHEMBL481257 | 0.80 | IDO1 (0.50) | MAOBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6156781 | 0.80 | CHRNA7 (0.43) | MAOBIDO1AGXTALDH1A1 | |
| SCHEMBL7218000 | 0.80 | GABRG2 (0.44) | GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9323171 | 0.80 | RAB9A (0.38) | GABRG2GABRB3GABRA5GABRA3NPC1 | |
| SCHEMBL12002543 | 0.79 | CYP17A1 (0.35) | IDO1AGXTCYP1A2 | |
| SCHEMBL12002629 | 0.78 | IDO1 (0.40) | MAOBRAB9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444889-A1 | Novel synthesis of carbapenem intermediates | MERCK & CO. INC. (US) | 1991-09-04 | — | — | EP | disclosed |