Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | THPO | P40225 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14984819 | 0.83 | KDM4E (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL3233945 | 0.81 | MAPT (0.88) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL9962914 | 0.79 | KDM4E (0.71) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL13295204 | 0.79 | KDM4E (0.71) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL13781427 | 0.79 | KDM4E (0.39) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL13630654 | 0.79 | MAPT (0.53) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL32679539 | 0.79 | KDM4E (0.53) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL5291 | 0.77 | MAPT (1.00) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL1384791 | 0.77 | MAPT (1.00) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL3923962 | 0.77 | MAPT (1.00) | MAPTKDM4ETHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323573-B2 | Production of polyketides | KOSAN BIOSCIENCES, INC. (US) | 2008-01-29 | — | — | US | disclosed |
| US-20070281343-A9 | Recombinant Myxococcus host cells used to produce polyketides, including epothilone and epothilone analogs; agriculture, chemistry, medicinal chemistry, medicine, molecular biology, and pharmacology | ARSLANIAN ROBERT L | 2007-12-06 | — | — | US | disclosed |
| US-20070092954-A1 | Production of polyketides | ARSLANIAN ROBERT L | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070092954-A1 | Production of polyketides | DHPS, MRPL21, FDFT1 | MAPT 3087/4885KDM4E 3237/4885THRB 1362/4885 |
| US-20070281343-A9 | Recombinant Myxococcus host cells used to produce polyketides, including epothilone and epothilone analogs; agriculture, chemistry, medicinal chemistry, medicine, molecular biology, and pharmacology | MRPL21, SQLE, DHPS | MAPT 2459/4885KDM4E 3233/4885THRB 509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.