Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPRG | P23470 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13903112 | 0.83 | LTA4H (0.48) | PTPRBPDE3BPDE3AP2RY12HPGD | |
| SCHEMBL11509018 | 0.82 | PTPRB (0.47) | PTPRBPTPN2PTPN1 | |
| SCHEMBL9591234 | 0.80 | NR1H4 (0.51) | EPHX2HPGD | |
| SCHEMBL8880437 | 0.80 | CYP4A11 (0.54) | PTPRBCYP4F2CYP4A11PTPRCPTPN2 | |
| SCHEMBL9689657 | 0.80 | MAOB (0.48) | EPHX2PDE3BPDE3AP2RY12HPGD | |
| SCHEMBL22921868 | 0.79 | TSHR (0.58) | EPHX2CYP4F2CYP4A11CYP4Z1TSHR | |
| SCHEMBL23200335 | 0.78 | HPGD (0.49) | EPHX2PDE3BPDE3AP2RY12HPGD | |
| SCHEMBL8879088 | 0.78 | MEN1 (0.44) | PTPRBCYP4F2CYP4A11PTPRCPTPN2 | |
| SCHEMBL17262795 | 0.78 | HPGD (0.49) | EPHX2PDE3BPDE3AP2RY12HPGD | |
| SCHEMBL2158877 | 0.78 | CALM1 (0.53) | EPHX2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335908-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONISTS | LILLY CO ELI (US) | 2008-02-13 | — | — | EP | disclosed |