Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | DPP4 | P27487 | 1/20 | 0.60 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | P4HB | P07237 | 2/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL656139 | 0.86 | LMNA (0.70) | LMNAKDM4EALDH1A1PKMPTPN5 | |
| SCHEMBL656140 | 0.86 | LMNA (0.70) | LMNAKDM4EALDH1A1PKMPTPN5 | |
| SCHEMBL1225514 | 0.86 | ALDH1A1 (0.62) | CHRNA7LMNAKDM4EALDH1A1PKM | |
| SCHEMBL1225517 | 0.86 | ALDH1A1 (0.62) | CHRNA7LMNAKDM4EALDH1A1PKM | |
| SCHEMBL11937142 | 0.86 | CHRNA7 (0.63) | CHRNA7LMNAKDM4EALDH1A1PKM | |
| SCHEMBL3064887 | 0.85 | MAPT (0.68) | CHRNA7LMNAKDM4EALDH1A1PKM | |
| SCHEMBL3064890 | 0.85 | MAPT (0.68) | CHRNA7LMNAKDM4EALDH1A1PKM | |
| SCHEMBL29406300 | 0.85 | MAPT (0.68) | CHRNA7LMNAKDM4EALDH1A1PKM | |
| SCHEMBL5915537 | 0.85 | LMNA (0.61) | CHRNA7LMNAKDM4EALDH1A1PKM | |
| SCHEMBL5915544 | 0.85 | LMNA (0.61) | CHRNA7LMNAKDM4EALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016738-A2 | ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-02-07 | — | — | WO | disclosed |