Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | P4HB | P07237 | 1/20 | 0.47 |
| ▸ | UNG | P13051 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5915544 | 1.00 | LMNA (0.61) | LMNAKDM4EALDH1A1PKMMAPT | |
| SCHEMBL14290443 | 0.85 | CHRNA7 (0.67) | LMNAKDM4EALDH1A1PKMMAPT | |
| SCHEMBL5915579 | 0.85 | LMNA (0.58) | LMNAKDM4EALDH1A1PKMMAPT | |
| SCHEMBL5915572 | 0.85 | LMNA (0.58) | LMNAKDM4EALDH1A1PKMMAPT | |
| SCHEMBL656140 | 0.83 | LMNA (0.70) | LMNAKDM4EALDH1A1PKMMAPT | |
| SCHEMBL656139 | 0.83 | LMNA (0.70) | LMNAKDM4EALDH1A1PKMMAPT | |
| SCHEMBL1225514 | 0.82 | ALDH1A1 (0.62) | LMNAKDM4EALDH1A1PKMMAPT | |
| SCHEMBL1225517 | 0.82 | ALDH1A1 (0.62) | LMNAKDM4EALDH1A1PKMMAPT | |
| SCHEMBL1225557 | 0.79 | LMNA (0.65) | LMNAKDM4EALDH1A1PKMMAPT | |
| SCHEMBL1225556 | 0.79 | LMNA (0.65) | LMNAKDM4EALDH1A1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060052600-A1 | Amino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-03-09 | — | — | US | disclosed |