Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1207170 | 0.94 | ALDH1A1 (0.43) | MAPTALDH1A1MEN1POLBKMT2A | |
| SCHEMBL14292395 | 0.93 | OPRK1 (0.39) | MAPTALDH1A1MEN1POLBKMT2A | |
| SCHEMBL12895474 | 0.90 | RORC (0.35) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL14293511 | 0.89 | ALDH1A1 (0.37) | MAPTALDH1A1MEN1POLBKMT2A | |
| SCHEMBL14292968 | 0.89 | MAPT (0.38) | MAPTALDH1A1MEN1POLBKMT2A | |
| SCHEMBL1208820 | 0.86 | ALDH1A1 (0.40) | MAPTALDH1A1MEN1POLBKMT2A | |
| SCHEMBL14293231 | 0.86 | ALDH1A1 (0.43) | MAPTALDH1A1MEN1POLBKMT2A | |
| SCHEMBL14293466 | 0.84 | MAPT (0.37) | MAPTALDH1A1POLBTP53LMNA | |
| SCHEMBL1208740 | 0.84 | MAPT (0.42) | MAPTALDH1A1MEN1POLBKMT2A | |
| SCHEMBL14293225 | 0.83 | RORC (0.39) | MAPTALDH1A1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020045-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | 4SC AG (DE) | 2008-02-21 | — | — | WO | disclosed |