Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14292424 | 0.94 | ALDH1A1 (0.41) | KDM4EALDH1A1RAB9ARORCTP53 | |
| SCHEMBL1207601 | 0.90 | MAPT (0.44) | KDM4EALDH1A1RAB9ATP53MAPT | |
| SCHEMBL14292425 | 0.88 | KDM4E (0.38) | KDM4EALDH1A1RAB9ARORCTP53 | |
| SCHEMBL12895522 | 0.87 | KDM4E (0.43) | KDM4EALDH1A1RAB9ATP53MAPT | |
| SCHEMBL14292417 | 0.86 | ALDH1A1 (0.38) | KDM4EALDH1A1RAB9ARORCTP53 | |
| SCHEMBL12895259 | 0.85 | KDM4E (0.42) | KDM4EALDH1A1RAB9ATP53MAPT | |
| SCHEMBL14293347 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1RAB9ARORCTP53 | |
| SCHEMBL14293194 | 0.84 | ALDH1A1 (0.40) | KDM4EALDH1A1RAB9ATP53MAPT | |
| SCHEMBL12895521 | 0.84 | ALDH1A1 (0.42) | KDM4EALDH1A1RAB9ATP53MAPT | |
| SCHEMBL1208667 | 0.84 | L3MBTL1 (0.44) | KDM4EALDH1A1RAB9ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020045-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | 4SC AG (DE) | 2008-02-21 | — | — | WO | disclosed |