Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14292424 | 0.91 | ALDH1A1 (0.41) | ALDH1A1MAPK1LMNARAB9AMAPT | |
| SCHEMBL1208691 | 0.89 | L3MBTL1 (0.48) | ALDH1A1LMNARAB9AMAPTTP53 | |
| SCHEMBL14292416 | 0.88 | RAB9A (0.41) | ALDH1A1MAPK1LMNARAB9AGALR3 | |
| SCHEMBL14293237 | 0.84 | KDM4E (0.42) | ALDH1A1LMNARAB9AMAPTTP53 | |
| SCHEMBL14292417 | 0.82 | ALDH1A1 (0.38) | ALDH1A1LMNARAB9AMAPTHSD17B10 | |
| SCHEMBL1208667 | 0.81 | L3MBTL1 (0.44) | ALDH1A1MAPK1LMNARAB9AMAPT | |
| SCHEMBL14293238 | 0.80 | L3MBTL1 (0.39) | ALDH1A1LMNARAB9AMAPTTP53 | |
| SCHEMBL14292911 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MAPK1LMNAMAPTTP53 | |
| SCHEMBL12895523 | 0.80 | RORC (0.40) | ALDH1A1RAB9AMAPTHSD17B10TP53 | |
| SCHEMBL14292988 | 0.80 | HPGD (0.44) | ALDH1A1LMNARAB9AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020045-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | 4SC AG (DE) | 2008-02-21 | — | — | WO | disclosed |