Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 5/20 | 0.51 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29809142 | 0.78 | BACE1 (0.57) | PTPRCCDC25BCDC25AKDM4EMEN1 | |
| SCHEMBL28277167 | 0.78 | BACE1 (0.57) | PTPRCCDC25BCDC25AKDM4EMEN1 | |
| SCHEMBL1408501 | 0.72 | BACE1 (0.64) | PTPRCCDC25BCDC25AKDM4EMEN1 | |
| SCHEMBL3444897 | 0.71 | CDC25B (0.57) | PTPRCCDC25BCDC25AKDM4EMEN1 | |
| SCHEMBL8849472 | 0.71 | PTPRC (0.61) | PTPRCCYP2E1CYP2A6CYP2B6CDC25B | |
| SCHEMBL28025950 | 0.70 | CYP2A6 (0.45) | PTPRCCYP2E1CYP2A6CYP2B6BCHE | |
| SCHEMBL28025951 | 0.69 | CYP2A6 (0.44) | PTPRCCYP2E1CYP2A6CYP2B6KDM4E | |
| SCHEMBL8401213 | 0.69 | CDC25A (0.44) | PTPRCCDC25BCDC25AKDM4EMEN1 | |
| SCHEMBL4946960 | 0.69 | CYP2A6 (0.64) | PTPRCCYP2E1CYP2A6CYP2B6MAOB | |
| SCHEMBL8240772 | 0.68 | BACE1 (0.48) | PTPRCCDC25BCDC25AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426212-A1 | Method for controlling NAD(P)/NAD(P)H ratio by oxidoreductase | Md Bioalpha Co., Ltd. (KR) | 2012-03-07 | — | — | EP | disclosed |