SCHEMBL28025951

SCHEMBL28025951

CC1=C(c2ccsc2)c2ccccc2[CH]1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.44
CYP2B6 P20813 2/20 0.44
CYP2E1 P05181 1/20 0.44
PTPRC P08575 2/20 0.42
MAOB P27338 1/20 0.40
STK10 O94804 2/20 0.35
SLK Q9H2G2 2/20 0.35
KCNH2 Q12809 1/20 0.34
TMIGD3 P0DMS9 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
EDNRA P25101 1/20 0.34
BCHE P06276 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
PDK2 Q15119 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28025979 0.79 ALDH1A1 (0.41) PTPRCKCNH2BCHECYP2C19KDM4E
SCHEMBL28219800 0.74 NAT1 (0.40) PTPRCADORA2ABCHECYP3A4CYP2C19
SCHEMBL8849472 0.73 PTPRC (0.61) CYP2A6CYP2B6CYP2E1PTPRCMAOB
SCHEMBL28025964 0.71 ALDH1A1 (0.41) MAOBADORA2AADORA1KDM4EMEN1
SCHEMBL4946960 0.71 CYP2A6 (0.64) CYP2A6CYP2B6CYP2E1PTPRCMAOB
SCHEMBL6320052 0.71 CYP2A6 (0.52) CYP2A6CYP2B6CYP2E1PTPRCMAOB
SCHEMBL28025428 0.70 GSTP1 (0.47) CYP2A6MAOBCYP3A4CYP2C9CYP2C19
SCHEMBL142992 0.69 PTPRC (0.51) CYP2A6CYP2B6CYP2E1PTPRCMAOB
SCHEMBL28025431 0.69 CYP2A6 (0.45) CYP2A6CYP2B6CYP2E1MAOBCYP3A4
SCHEMBL30165237 0.67 CYP2A6 (0.52) CYP2A6CYP2B6CYP2E1PTPRCMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed
CN-104822697-A Bridged metallocene compounds, catalyst systems and polymerization processes using the same EXXONMOBIL CHEM PATENTS INC 2015-08-05 CN disclosed