Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5076754 | 0.76 | ALDH1A1 (0.41) | CYP2A6PTPRCMAOB | |
| SCHEMBL5824297 | 0.75 | MEN1 (0.32) | PTPRCBCHE | |
| SCHEMBL28303649 | 0.74 | ALDH1A1 (0.39) | CYP2A6PTPRCMAOB | |
| SCHEMBL4946960 | 0.73 | CYP2A6 (0.64) | CYP2A6CYP2B6CYP2E1PTPRCCYP3A4 | |
| SCHEMBL28515419 | 0.71 | NPC1 (0.39) | PDK2KCNH2 | |
| SCHEMBL142992 | 0.70 | PTPRC (0.51) | CYP2A6CYP2B6CYP2E1PTPRCMAOB | |
| SCHEMBL28025982 | 0.69 | CYP1A2 (0.43) | CYP2C19MAOB | |
| SCHEMBL27502471 | 0.69 | ALDH1A1 (0.35) | CYP2A6PTPRC | |
| SCHEMBL28219408 | 0.69 | ALDH1A1 (0.36) | CYP2A6 | |
| SCHEMBL28025966 | 0.69 | PTGS2 (0.38) | MAOBPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137729-B | Catalysts for forming multimodal polymers | 埃克森美孚化学专利公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-109824802-A | Metallocenic compound, catalyst system and the polymerization using them of bridging | 埃克森美孚化学专利公司 | 2019-05-31 | — | — | CN | disclosed |
| CN-104822697-A | Bridged metallocene compounds, catalyst systems and polymerization processes using the same | EXXONMOBIL CHEM PATENTS INC | 2015-08-05 | — | — | CN | disclosed |