Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | RECQL | P46063 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | ELANE | P08246 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459324 | 0.80 | APAF1 (0.60) | MAOAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL5818633 | 0.79 | MAOA (0.78) | MAOAMAPTALDH1A1MAPK1TDP1 | |
| Anthrarufin SCHEMBL29363946 | 0.77 | MAOA (1.00) | MAOAMAPTALDH1A1MAPK1TDP1 | |
| Anthrarufin SCHEMBL29874705 | 0.77 | MAOA (1.00) | MAOAMAPTALDH1A1MAPK1TDP1 | |
| Anthrarufin SCHEMBL187843 | 0.77 | MAOA (1.00) | MAOAMAPTALDH1A1MAPK1TDP1 | |
| Droserone SCHEMBL5858407 | 0.77 | MAOA (0.67) | MAOAMAPTALDH1A1MAPK1TDP1 | |
| Droserone SCHEMBL30003199 | 0.77 | MAOA (0.67) | MAOAMAPTALDH1A1MAPK1TDP1 | |
| Danthron SCHEMBL30544826 | 0.75 | MAPT (1.00) | MAOAMAPTALDH1A1MAPK1TDP1 | |
| Anthrarufin SCHEMBL28419741 | 0.75 | MAOA (0.95) | MAOAMAPTALDH1A1MAPK1TDP1 | |
| Danthron SCHEMBL29356886 | 0.75 | MAPT (1.00) | MAOAMAPTALDH1A1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008033-A1 | THE USE OF NAPHTOQUINONES IN THE TREATMENT AND CONTROL OF DIABETES, INSULIN RESISTANCE AND HYPERGLYCEMIA | GLUCOX BIOTECH AB (SE) | 2008-01-17 | — | — | WO | disclosed |