Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 4/20 | 0.46 |
| ▸ | S100A4 | P26447 | 3/20 | 0.46 |
| ▸ | CDC25A | P30304 | 3/20 | 0.46 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571005 | 0.86 | MAPT (0.53) | CDC25BS100A4CDC25AMAP2K7MAPT | |
| SCHEMBL14236650 | 0.81 | DHODH (0.68) | CDC25BS100A4CDC25AMAP2K7DHODH | |
| SCHEMBL14307223 | 0.81 | CDC25B (0.50) | CDC25BS100A4CDC25AMAP2K7DHODH | |
| SCHEMBL14190490 | 0.80 | DHODH (0.41) | CDC25BS100A4CDC25AMAP2K7DHODH | |
| SCHEMBL14307224 | 0.76 | FGFR1 (0.49) | CDC25BS100A4CDC25AMAP2K7DHODH | |
| SCHEMBL571120 | 0.76 | PKM (0.54) | CDC25BS100A4CDC25AMAP2K7MAPT | |
| SCHEMBL5820368 | 0.75 | MAPT (0.58) | CDC25BS100A4CDC25AMAP2K7MAPT | |
| SCHEMBL12761936 | 0.75 | TBXAS1 (0.47) | CDC25BS100A4CDC25AMAP2K7MAPT | |
| SCHEMBL14160413 | 0.75 | PTPN1 (0.39) | CDC25BS100A4CDC25AMAP2K7DHODH | |
| SCHEMBL572112 | 0.74 | ALDH1A1 (0.56) | CDC25BS100A4CDC25AMAP2K7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006088315-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OR PREVENTION OF DISEASES INVOLVING OBESITY, DIABETES, METABOLIC SYNDROME, NEURO-DEGENERATIVE DISEASES AND MITOCHONDRIA DYSFUNCTION DISEASES | MD BIOALPHA CO., LTD. (KR) | 2006-08-24 | — | — | WO | disclosed |