Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045378 | 0.83 | KMT2A (0.70) | HPGDKMT2AALDH1A1LMNATP53 | |
| SCHEMBL9302790 | 0.82 | HPGD (1.00) | HPGDKMT2AALDH1A1LMNATP53 | |
| SCHEMBL21490289 | 0.72 | SLC9A1 (0.75) | HPGDKMT2AALDH1A1LMNATP53 | |
| SCHEMBL30368818 | 0.71 | GAA (0.66) | HPGDKMT2AALDH1A1LMNATP53 | |
| SCHEMBL9305191 | 0.71 | GAA (0.66) | HPGDKMT2AALDH1A1LMNATP53 | |
| SCHEMBL3552907 | 0.70 | KCNMA1 (0.67) | HPGDKMT2AALDH1A1LMNATP53 | |
| SCHEMBL9303187 | 0.70 | KCNMA1 (0.67) | HPGDKMT2AALDH1A1LMNATP53 | |
| SCHEMBL2734889 | 0.69 | GRM2 (1.00) | ALDH1A1KCNMA1SLC9A1GRM2MAPT | |
| SCHEMBL3259919 | 0.68 | SLC9A1 (0.66) | HPGDTSHRKCNMA1SLC9A1GRM2 | |
| SCHEMBL31234269 | 0.68 | SLC9A1 (0.70) | HPGDTSHRKCNMA1SLC9A1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008006449-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2008-01-17 | — | — | WO | disclosed |