Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.61 |
| ▸ | BRD4 | O60885 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14307551 | 0.83 | HPGD (0.70) | KMT2AALDH1A1LMNAHPGDTP53 | |
| SCHEMBL9302790 | 0.82 | HPGD (1.00) | KMT2AALDH1A1LMNAHPGDTP53 | |
| SCHEMBL3878065 | 0.78 | KCNMA1 (0.80) | KMT2AALDH1A1LMNAHPGDTP53 | |
| SCHEMBL20815428 | 0.74 | KCNMA1 (0.64) | KMT2AALDH1A1LMNAHPGDTP53 | |
| SCHEMBL27787691 | 0.72 | ATM (0.64) | KMT2AALDH1A1LMNAHPGDTP53 | |
| SCHEMBL9305191 | 0.71 | GAA (0.66) | KMT2AALDH1A1LMNAHPGDTP53 | |
| SCHEMBL30368818 | 0.71 | GAA (0.66) | KMT2AALDH1A1LMNAHPGDTP53 | |
| SCHEMBL31558359 | 0.70 | KDM4E (0.50) | KMT2AALDH1A1LMNAHPGDTP53 | |
| SCHEMBL3552907 | 0.70 | KCNMA1 (0.67) | KMT2AALDH1A1LMNAHPGDTP53 | |
| SCHEMBL9303187 | 0.70 | KCNMA1 (0.67) | KMT2AALDH1A1LMNAHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825172-B1 | Synthesis of 1-acetoxy-2-methylnaphthalene | BRISTOL MYERS SQUIBB CO (US) | 2000-04-26 | — | — | EP | disclosed |
| EP-0825172-A1 | Synthesis of 1-acetoxy-2-methylnaphthalene | Bristol-Myers Squibb Company (US) | 1998-02-25 | — | — | EP | disclosed |
| US-5670698-A | Synthesis of 1-acetoxy-2-methylnaphthalene | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-09-23 | — | — | US | disclosed |